It goes without saying that being the CEO of any sort of organization comes with a lot of responsibilities. CEOs are not only responsible for all employees and stakeholders, but also serve as the public face of an organization. This holds true for the CEOs of nonprofits as well. Although only 6% of the overall S&P 500 CEOs are female, 45% of non-profit CEOs are women. These non-profits may be on to something, as a study shows that financial performance is better for companies with more women in leadership roles.

Unfortunately, the women who hold these top positions usually make less money than their male counterparts, with female CEOs receiving 21% less. This gender pay gap may continue to change as time progresses however, as millennials look at their careers in new ways. They are less interested in job titles than the difference they’re actually making, not falling into the typical philanthropy model. Although time will tell what the future of this industry holds, let’s take a look at the women currently running the non-profit game.

Melinda Gates, Bill & Melinda Gates Foundation
The wife of Bill Gates, the founder of Microsoft, Melinda serves as the co-chair of her and husband’s foundation. The foundation has currently donated $41.3 billion to help people lead healthy productive lives.

Christine Lagarde, IMF
Christine, a French lawyer and politician, is the managing director of the International Monetary Fund. Through the organization, she works to bring economic discipline to countries around the globe.

Laurene Powell Jobs, Emerson Collective
The widow of Steve Jobs, Laurene is the chair of Emerson Collective, which uses entrepreneurship for social reform and to help needy students. She has a net worth of over $19 billion.

Priscilla Chan, Chan Zuckerberg Initiative
Married to Mark Zuckerberg, Priscilla is the cofounder of the Chan Zuckerberg Initiative, which seeks to advance human potential and promote equal opportunity.

Fabiola Gianotti, CERN
Fabiola, a research physicist, is the director-general of CERN, where she works to uncover the secrets of the universe.

Patricia Harris, Bloomberg Philanthropies
As CEO of the non-profit, Patricia focuses on health, the environment and education. Current investments seek to eradicate polio and malaria.

Drew Gilpin Faust, Harvard University
The president of Harvard University, Drew leads a faculty of over 2,000 and handles an endowment of $37.6 billion.

Eliza Manningham-Buller, Wellcome Trust
Eliza manages one of the biggest pharmaceutical trusts in the world. They recently announced that they will donate over $1 billion in 2017-18.